Cerebral Amyloid Angiopathy

A heterogeneous group of sporadic or familial disorders characterized by AMYLOID deposits in the walls of small and medium sized blood vessels of CEREBRAL CORTEX and MENINGES. Clinical features include multiple, small lobar CEREBRAL HEMORRHAGE; cerebral ischemia (BRAIN ISCHEMIA); and CEREBRAL INFARCTION. Cerebral amyloid angiopathy is unrelated to generalized AMYLOIDOSIS. Amyloidogenic peptides in this condition are nearly always the same ones found in ALZHEIMER DISEASE. (from Kumar: Robbins and Cotran: Pathologic Basis of Disease, 7th ed., 2005)

Also Known As:

Congophilic Angiopathy; Angiopathy, Cerebral Amyloid; Angiopathy, Congophilic; Cerebral Amyloid Angiopathies; Congophilic Angiopathies; Amyloid Angiopathy, Cerebral; Sporadic Cerebral Amyloid Angiopathy

Nervous System Diseases: 14737
- Central Nervous System Diseases: 4371
  - Brain Diseases: 16141
    - Cerebrovascular Disorders: 7764
      - Intracranial Arterial Diseases: 8
        Cerebral Arterial Diseases: 27
        Cerebral Amyloid Angiopathy: 1444
Cardiovascular Diseases: 94258
- Vascular Diseases: 15340
  - Cerebrovascular Disorders: 7764
    - Intracranial Arterial Diseases: 8
      - Cerebral Arterial Diseases: 27
        Cerebral Amyloid Angiopathy: 1444
Nutritional and Metabolic Diseases: 15
- Metabolic Diseases: 10634
  - Proteostasis Deficiencies: 1476
    - Amyloidosis: 11961
      - Cerebral Amyloid Angiopathy: 1444

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Drug/Important Bio-Agent (IBA)